CIB1 (clone 5A1F5E12, 5A1H7E12), anti-human
€394.00
In stock
SKU
252667
Catalog Nr.: 252667
Size: 0.1 ml
Isotype:
Applications: WB, IHC
Size: 0.1 ml
Isotype:
Applications: WB, IHC
Protein Family: Chaperones and Folding Catalysts
Pathway and Disease: Signaling Molecules and Interaction
Description:
CIB1 (Calcium and integrin binding 1) is a 191-amino acid protein (~21kDa), belongs to the calcium-binding protein family. CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function. CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.
Alternate Names: Calcium and integrin-binding protein 1, CIB, Calcium- and integrin-binding protein, CIBP, Calmyrin, DNA-PKcs-interacting protein, Kinase-interacting protein, KIP, SNK-interacting protein 2-28, SIP2-28, CIB, KIP, PRKDCIP, CIB1
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: Q99828
Antigen: Purified recombinant fragment of CIB1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
CIB1 (Calcium and integrin binding 1) is a 191-amino acid protein (~21kDa), belongs to the calcium-binding protein family. CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function. CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.
Alternate Names: Calcium and integrin-binding protein 1, CIB, Calcium- and integrin-binding protein, CIBP, Calmyrin, DNA-PKcs-interacting protein, Kinase-interacting protein, KIP, SNK-interacting protein 2-28, SIP2-28, CIB, KIP, PRKDCIP, CIB1
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: Q99828
Antigen: Purified recombinant fragment of CIB1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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