Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody

Background:
caspase 2(CASP2) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],

Alternative Names:
CASP2, ICH1, NEDD2, Caspase-2, Caspase 2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1

Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 2. AA range:276-325

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 22

GeneID: CASP2

Storage: -20°C/1 year

NOTE: For Research Use Only