Cleaved-Cathepsin L1 HC (T288) Polyclonal Antibody

Background:
cathepsin L(CTSL) Homo sapiens The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012],

Alternative Names:
CTSL1, CTSL, Cathepsin L1, Major excreted protein, MEP

Immunogen: The antiserum was produced against synthesized peptide derived from human CATL1. AA range:239-288

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 30

GeneID: CTSL1

Storage: -20°C/1 year

NOTE: For Research Use Only