Cleaved-MMP-3 (F100) Polyclonal Antibody

Background:
matrix metallopeptidase 3(MMP3) Homo sapiens Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008],

Alternative Names:
MMP3, STMY1, Stromelysin-1, SL-1, Matrix metalloproteinase-3, MMP-3, Transin-1

Immunogen: The antiserum was produced against synthesized peptide derived from human MMP3. AA range:81-130

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 43

GeneID: MMP3

Storage: -20°C/1 year

NOTE: For Research Use Only