CNPase polyclonal, anti-human, mouse, rat

Protein Family: Enzymes

Pathway and Disease: Nervous and Sensory Systems, Nucleotide Metabolism

Description:
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNPase A) is a phosphodiesterase that catalyzes the following reaction: Nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate. CNPase is present in very high levels in brain and peripheral nerve. This enzyme is found almost exclusively in oligo-dendrocytes and Schwann cells, the cells that form myelin in the central and peripheral nervous system, respectively. Therefore, CNPase has been very useful as a marker for these particular cell types.

Alternate Names: CNP, CNPase, 2', 3'-cyclic-nucleotide 3'-phosphodiesterase

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P09543

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CNPase.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.1 mg/ml BSA, 25% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.