Collagen V polyclonal, anti-human, mouse, rat, bovine, pig, dog, chicken
€362.00
In stock
SKU
251202
Catalog Nr.: 251202
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Signal Transduction, Endocrine System
Description:
Collagen type V collagen (collagen V) is a member of group I collagen (fibrillar forming collagen). Collagen V is a minor connective tissue component of nearly ubiquitous distribution. Collagen V binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Defects in COL5A1 are a cause of Ehlers-Danlos syndrome type 1 (EDS1), also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity.
Alternate Names: Collagen alpha-1(V) chain, COL5A1, Collagen V, Collagen type V
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P20908
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human collagen V.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Calvi En et al. 2014. Hernia. PMID# 24415040.
Pathway and Disease: Signal Transduction, Endocrine System
Description:
Collagen type V collagen (collagen V) is a member of group I collagen (fibrillar forming collagen). Collagen V is a minor connective tissue component of nearly ubiquitous distribution. Collagen V binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Defects in COL5A1 are a cause of Ehlers-Danlos syndrome type 1 (EDS1), also known as Ehlers-Danlos syndrome gravis or severe classic type Ehlers-Danlos syndrome. EDS is a connective tissue disorder characterized by hyperextensible skin, atrophic cutaneous scars due to tissue fragility and joint hyperlaxity.
Alternate Names: Collagen alpha-1(V) chain, COL5A1, Collagen V, Collagen type V
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P20908
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human collagen V.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Calvi En et al. 2014. Hernia. PMID# 24415040.
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