Collagen VI polyclonal, anti-human, mouse, rat, bovine, pig, dog, chicken

Protein Family: CAM Ligands

Pathway and Disease: Signaling Molecules and Interaction, Cell Communication

Description:
Collagen VI acts as a cell-binding protein. Collagen VI is a trimer composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI). Defects in collagen VI are a cause of Bethlem myopathy (BM). BM is a rare autosomal dominant proximal myopathy characterized by early childhood onset (complete penetrance by the age of 5) and joint contractures most frequently affecting the elbows and ankles.

Alternate Names: Collagen VI, Collagen Type VI, Collagen alpha-1(VI) chain, COL6A1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P12109

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human collagen VI.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.