Connexin-26 polyclonal, anti-human, mouse, rat
€347.00
In stock
SKU
251846
Catalog Nr.: 251846
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, ICC
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, ICC
Protein Family: Receptors and Channels
Pathway and Disease: Membrane Transport, Nervous and Sensory Systems
Description:
Gap junction beta-2 protein (connexin-26) is a transmembrane channel that, together with other connexins, forms a gap junction. Gap junctions allow low MW materials to flow from one cell to a neighboring cell. Defects in connexin-26 are the cause of deafness autosomal recessive type 1A (DFNB1A). DFNB1A is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
Alternate Names: Connexin-26, Gap junction beta-2 protein, Cx26, GJB2
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500
Accession No.: P21994
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of rat connexin-26.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 50% glycerol with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Membrane Transport, Nervous and Sensory Systems
Description:
Gap junction beta-2 protein (connexin-26) is a transmembrane channel that, together with other connexins, forms a gap junction. Gap junctions allow low MW materials to flow from one cell to a neighboring cell. Defects in connexin-26 are the cause of deafness autosomal recessive type 1A (DFNB1A). DFNB1A is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
Alternate Names: Connexin-26, Gap junction beta-2 protein, Cx26, GJB2
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500
Accession No.: P21994
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of rat connexin-26.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 50% glycerol with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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