CREB-1 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors

Pathway and Disease: Endocrine System, Cancers, Immune System, Transcription

Description:
CREB-1 binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. CREB-1 has been implicated in synchronization of circadian rhythmicity.

Alternate Names: cAMP response element-binding protein, CREB, CREB1, CREB-1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500

Accession No.: P16220

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CREB1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.