CD115 (CSF1R) polyclonal, anti-human, mouse

CD115 (CSF1R) polyclonal, anti-human, mouse

€388.00
In stock
SKU
BS71419
Catalog Number: BS71419
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB

Datasheet
Background:
c-Fms/CSF-1R is a transmembrane tyrosine kinase receptor belonging to the CSF1/PDGF receptor family. It is encoded by the c-Fms proto-oncogene and is expressed in mononuclear phagocytes, oocytes, decidual cells, trophoblastic cells and some myoblasts. It is important for growth and differentiation of myeloid cells and its function can be regulated by SLAP-2. c-Fms/CSF-1R is responsible for mediating all of the functions of M-CSF. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages.

Alternative Name:
FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, M-CSF-R

Application Dilution: WB: 1:500 - 1:2000

Specificity: CSF1R polyclonal antibody detects endogenous levels of CSF1R protein.

Immunogen:
A synthetic peptide of human CSF1R.

MW: ~ 108 kDa

Swis Prot.: P07333

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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