CD116 (CSF2RA) polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS6570
Background:
The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common β subunit. The a subunits are low affinity ligand binding proteins while the β subunits do not themselves bind ligand, but are required for high affinity binding by the a subunits. In contrast, the mouse IL-3 receptor has two distinct β subunits, one that functions only in IL-3 mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine β-subunits are 91% homologous at the amino acid level but only 56% homologous to the human β subunit. Although neither the murine nor the human β subunit contains tyrosine kinase domains, both activate tyrosine phosphorylation mediated signaling pathways.
Alternative Name:
CD116, CD116 antigen, CDw116, Colony stimulating factor 2 receptor alpha chain, CSF 2R, CSF2R, CSF2RA, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM CSF R alpha, GM CSF receptor alpha subunit, GM-CSF-R-alpha, GMCSFR, GMCSFR-alpha, GMR-alpha, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: CSF2RA polyclonal antibody detects endogenous levels of CSF2RA protein.
Immunogen:
Recombinant full length Human CSF2RA.
MW: ~ 46 kDa
Swis Prot.: P15509
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common β subunit. The a subunits are low affinity ligand binding proteins while the β subunits do not themselves bind ligand, but are required for high affinity binding by the a subunits. In contrast, the mouse IL-3 receptor has two distinct β subunits, one that functions only in IL-3 mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine β-subunits are 91% homologous at the amino acid level but only 56% homologous to the human β subunit. Although neither the murine nor the human β subunit contains tyrosine kinase domains, both activate tyrosine phosphorylation mediated signaling pathways.
Alternative Name:
CD116, CD116 antigen, CDw116, Colony stimulating factor 2 receptor alpha chain, CSF 2R, CSF2R, CSF2RA, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM CSF R alpha, GM CSF receptor alpha subunit, GM-CSF-R-alpha, GMCSFR, GMCSFR-alpha, GMR-alpha, Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: CSF2RA polyclonal antibody detects endogenous levels of CSF2RA protein.
Immunogen:
Recombinant full length Human CSF2RA.
MW: ~ 46 kDa
Swis Prot.: P15509
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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