Cyclin B1 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors

Pathway and Disease: Endocrine System, Cell Growth and Death

Description:
G2/mitotic-specific cyclin-B1(cyclin B1) is essential for the control of the cell cycle at the G2/M (mitosis) transition. Cyclin B1 interacts with the CDC2 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). Cyclin B1 accumulates steadily during G2 and is abruptly destroyed at mitosis.

Alternate Names: Cyclin B1, Cyclin-B1, G2/mitotic-specific cyclin-B1, CCNB1, CCNB

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; FC: 1:100-1:500

Accession No.: P14635

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human cyclin B1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.