Cyclin H (clone ), anti-human
€388.00
In stock
SKU
MB0018
Background:
Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.
Alternative Name:
Cyclin-H, MO15-associated protein, p34, p37, CCNH
Application Dilution: WB: 1:1000, IP: 1:50~1:200
Specificity: This antibody detects endogenous levels of CCNH and does not cross-react with related proteins
Immunogen:
Recombinant full length Human Cyclin H.
MW: Predicted band size: 38KDa, Observed band size: 38KDa
Swis Prot.: P51946
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.
Alternative Name:
Cyclin-H, MO15-associated protein, p34, p37, CCNH
Application Dilution: WB: 1:1000, IP: 1:50~1:200
Specificity: This antibody detects endogenous levels of CCNH and does not cross-react with related proteins
Immunogen:
Recombinant full length Human Cyclin H.
MW: Predicted band size: 38KDa, Observed band size: 38KDa
Swis Prot.: P51946
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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