CYLD polyclonal, anti-human, mouse

Protein Family: Enzymes, Peptidases, Ubiquitins

Pathway and Disease: Cancers, Signaling Molecules and Interaction

Description:
CYLD is a negative regulator of TRAF2 and NF-kappa B signaling pathway. CYLD has a deubiquitinating activity that is directed towards non-Lys48-linked polyubiquitin chains. Defects in CYLD are the cause of familial cylindromatosis, a highly tumor type-specific disorder.

Alternate Names: Probable ubiquitin carboxyl-terminal hydrolase CYLD, Ubiquitin thioesterase CYLD, Ubiquitin-specific-processing protease CYLD, Deubiquitinating enzyme CYLD, CYLD1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500

Accession No.: Q9NQC7

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CYLD.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 17% glycerol with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.