CYR61 (rodent) polyclonal, anti-human, mouse, rat

Protein Family: CAM Ligands

Pathway and Disease: Cell Growth and Death

Description:
Cysteine-rich angiogenic inducer 61 (CYR61) promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. CYR61 appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5.

Alternate Names: Protein CYR61, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, IGF-binding protein 10, IGFBP-10, IBP-10, Protein GIG1, CCN family member 1, CCN1, GIG1, IGFBP10

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: O00622

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CYR61.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.