Cytokeratin-4 polyclonal, anti-human, mouse, rat, bovine, horse, dog
€347.00
In stock
SKU
251382
Catalog Nr.: 251382
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IP
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IP
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Signaling Molecules and Interaction, Cell Growth and Death
Description:
Keratin, type II cytoskeletal 4 (cytokeratin-4) is a heterotetramer composed of two type I and two type II keratins. Cytokeratin-4 is generally associated with keratin-13. Defects in cytokeratin-4 are a cause of white sponge nevus of cannon (WSN). WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa.
Alternate Names: Cytokeratin-4, Keratin, type II cytoskeletal 4, CK-4, Keratin-4, K4, KRT4
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500
Accession No.: P19013
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human cytokeratin-4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Cell Growth and Death
Description:
Keratin, type II cytoskeletal 4 (cytokeratin-4) is a heterotetramer composed of two type I and two type II keratins. Cytokeratin-4 is generally associated with keratin-13. Defects in cytokeratin-4 are a cause of white sponge nevus of cannon (WSN). WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa.
Alternate Names: Cytokeratin-4, Keratin, type II cytoskeletal 4, CK-4, Keratin-4, K4, KRT4
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500
Accession No.: P19013
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human cytokeratin-4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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