Cytokeratin-8 polyclonal, anti-human, mouse, rat, xenopus, dog, pig, zebrafish, bovine, chimpanzee, monkey, cat

Protein Family: Cytoskeleton Proteins

Pathway and Disease: Signaling Molecules and Interaction, Cell Communication

Description:
Cytokeratin-8 (Type II cytoskeletal keratin 8), together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. Cytokeratin-8 is a heterotetramer of two type I and two type II keratins. Defects in cytokeratin-8 are a cause of cirrhosis (CIRRH).

Alternate Names: CK-8, Cytokeratin-8, Keratin, type II cytoskeletal 8, CK-8, Keratin-8, K8, KRT8, CYK8

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P05787

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human cytokeratin-8.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.