(DANRE) sh3bp4a Blocking Peptide (N-term)
€363.00
In stock
SKU
AC-BP21084a
Background:
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).
Other Names:
SH3 domain-binding protein 4-A, sh3bp4a, sh3bp4
Target/Specificity:
The synthetic peptide sequence is selected from aa 132-145 of HUMAN sh3bp4a
Gene Name: sh3bp4a
Gene ID: 403082
Primary Accession: Q1LVQ2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Possible role in regulating endocytosis of the transferrin receptor at the plasma membrane. Alternatively, may function as a negative regulator of the amino acid-induced TOR signaling by inhibiting the formation of active Rag GTPase complexes. Preferentially binds inactive Rag GTPase complexes and prevents their interaction with the mTORC1 complex inhibiting its relocalization to lysosomes and its activation. Thereby, may indirectly regulate cell growth, proliferation and autophagy (By similarity).
Other Names:
SH3 domain-binding protein 4-A, sh3bp4a, sh3bp4
Target/Specificity:
The synthetic peptide sequence is selected from aa 132-145 of HUMAN sh3bp4a
Gene Name: sh3bp4a
Gene ID: 403082
Primary Accession: Q1LVQ2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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