(DANRE) tie2 polyclonal (N-term), anti-zebrafish

Background:
Tyrosine-protein kinase that acts as cell-surface receptor for angiopoietins and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Can activate or inhibit angiogenesis, depending on the context. Angiopoietin signaling triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors (By similarity).

Other Names:
Tyrosine-protein kinase receptor Tie-2, Tyrosine kinase with Ig and EGF homology domains-2, tie2, tie-2

Target/Specificity:
This (DANRE) tie2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 160-194 amino acids from the N-terminal region of DANRE tie2.

Antigen Region:
160-194

Gene Name: tek {ECO:0000250|UniProtKB:Q02763}
Gene ID: 30747
Primary Accession: O73791
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.