DAT polyclonal, anti-human

Protein Family: Enzymes

Pathway and Disease: Amino Acid Metabolism

Description:
The dopamine transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse. Levels of DAT protein expression are altered by chronic drug administration.

Alternate Names: Sodium-dependent dopamine transporter, DA transporter, DAT, Solute carrier family 6 member 3, SLC6A3, DAT2

Application Notes: E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:1,000

Accession No.: Q01959

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human dopamine transporter (extracellular loop 2).

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.