DDC polyclonal, anti-human, mouse, rat, guinea pig, pig, bovine, monkey, dog

Protein Family: Enzymes

Pathway and Disease: Amino Acid Metabolism

Description:
DOPA decarboxylase (DDC) catalyzes the decarboxylation of L-3, 4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in DDC are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) causing developmental and psychomotor delay.

Alternate Names: Aromatic-L-amino-acid decarboxylase, AADC, DOPA decarboxylase, DDC

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P20711

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DDC.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.