Delangin-A polyclonal, anti-human, mouse, rat
€354.00
In stock
SKU
250133
Catalog Nr.: 250133
Size: 0.1 mg
Isotype: Rat IgG1
Applications: E, WB, IP, IF, IHC
Size: 0.1 mg
Isotype: Rat IgG1
Applications: E, WB, IP, IF, IHC
Protein Family: Chaperones and Folding Catalysts
Pathway and Disease: Development and Behavior, Replication and Repair
Description:
Delangin (NIPBL) plays a structural role in chromatin cohesion, likely by interacting with the cohesin complex. Delangin deficiencies are the cause of Cornelia de Lange syndrome type 1 (CDLS1), which is a heterogeneous developmental disorder associated with malformations affecting multiple systems such as member growth, cognitive retardation, cardiac anomalies. This antibody recognizes the isoform A (long form) of human and mouse delangin in Western blot, immunoprecipitation, immunofluorescent staining and immunohistochemistry.
Alternate Names: Nipped-B-like protein, Delangin, SCC2 homolog, NIPBL, IDN3A
Application Notes: E: 1:10,000; WB: 1 ug/ml; IP: 2 ug/ml; IF: 10 ug/ml; IHC: 2 ug/ml
Accession No.: Q6KC79
Antigen: Synthetic peptide encompassing a sequence within the C-term region of human delangin protein coupled to BSA
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Abboud N et al. 2015 Nat Commun. 6: 6749. PMID 25851587.
Pathway and Disease: Development and Behavior, Replication and Repair
Description:
Delangin (NIPBL) plays a structural role in chromatin cohesion, likely by interacting with the cohesin complex. Delangin deficiencies are the cause of Cornelia de Lange syndrome type 1 (CDLS1), which is a heterogeneous developmental disorder associated with malformations affecting multiple systems such as member growth, cognitive retardation, cardiac anomalies. This antibody recognizes the isoform A (long form) of human and mouse delangin in Western blot, immunoprecipitation, immunofluorescent staining and immunohistochemistry.
Alternate Names: Nipped-B-like protein, Delangin, SCC2 homolog, NIPBL, IDN3A
Application Notes: E: 1:10,000; WB: 1 ug/ml; IP: 2 ug/ml; IF: 10 ug/ml; IHC: 2 ug/ml
Accession No.: Q6KC79
Antigen: Synthetic peptide encompassing a sequence within the C-term region of human delangin protein coupled to BSA
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Abboud N et al. 2015 Nat Commun. 6: 6749. PMID 25851587.
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