Delangin-B (clone KT55), anti-human, mouse

Protein Family: Chaperones and Folding Catalysts

Pathway and Disease: Development and Behavior, Replication and Repair

Description:
Delangin (NPBL) plays a structural role in chromatin cohesion, likely by interacting with the cohesin complex. Delangin deficiencies are the cause of Cornelia de Lange syndrome type 1 (CDLS1), which is a heterogeneous developmental disorder associated with malformations affecting multiple systems such as member growth, cognitive retardation, cardiac anomalies. This antibody recognizes the isoform B (short form) of human and mouse delangin in Western blot, immunoprecipitation, immunofluorescent staining and immunohistochemistry.

Alternate Names: Nipped-B-like protein, Delangin, SCC2 homolog, NIPBL, IDN3B

Application Notes: WB: 1:1,000

Accession No.: Q6KC79, NP_056199

Antigen: Synthetic peptide encompassing a sequence within the C-term region of human delangin protein coupled to BSA

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.