DiMethyl-DNMT3A-K44 Polyclonal Antibody

Background:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

Synonyms:
Dnmt3a, MmuIIIA, DNMT3A2, M.HsaIIIA, TBRS

Immunogen: A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_031898.1).

Swissprot: O88508
Gene ID: 13435

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.