Dynamin-1 (clone 3G4B6), anti-human
€491.00
In stock
SKU
252653
Catalog Nr.: 252653
Size: 0.1 ml
Isotype: Mouse IgG2a
Applications: WB, IHC
Size: 0.1 ml
Isotype: Mouse IgG2a
Applications: WB, IHC
Protein Family: Transporters
Pathway and Disease: Immune System, Infectious Diseases
Description:
Dyn1 (Dynamin-1) is a 864-amino acid protein (~95kDa) belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain and lungs), constitute the dynamin family. Members of the dynamin family are GPTases, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.
Alternate Names: Dynamin-1, DNM, DNM1
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: Q05193
Antigen: Purified recombinant fragment of human Dynamin-1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System, Infectious Diseases
Description:
Dyn1 (Dynamin-1) is a 864-amino acid protein (~95kDa) belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain and lungs), constitute the dynamin family. Members of the dynamin family are GPTases, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.
Alternate Names: Dynamin-1, DNM, DNM1
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: Q05193
Antigen: Purified recombinant fragment of human Dynamin-1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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