Dynamin-2 (clone 5E4C2F3), anti-human
€443.00
In stock
SKU
252686
Catalog Nr.: 252686
Size: 0.1 ml
Isotype: Mouse IgG2a
Applications: WB, IHC
Size: 0.1 ml
Isotype: Mouse IgG2a
Applications: WB, IHC
Protein Family: Enzymes
Pathway and Disease: Immune System, Nervous and Sensory Systems, Infectious Diseases
Description:
Dynamin-2 is a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Dynamin-2 is involved in vesicular trafficking processes, in particular endocytosis. Defects in dynamin-2 are a cause of centronuclear myopathy autosomal dominant (ADCNM), also known as autosomal dominant myotubular myopathy. Centronuclear myopathies (CNMs) are congenital muscle disorders characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk and neck muscles.
Alternate Names: Dynamin-2, DYN2, DYNII, CMTDI1, CMTDIB, DI-CMTB, DNM2
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: P50570
Antigen: Purified recombinant fragment of Dynamin-2 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System, Nervous and Sensory Systems, Infectious Diseases
Description:
Dynamin-2 is a microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Dynamin-2 is involved in vesicular trafficking processes, in particular endocytosis. Defects in dynamin-2 are a cause of centronuclear myopathy autosomal dominant (ADCNM), also known as autosomal dominant myotubular myopathy. Centronuclear myopathies (CNMs) are congenital muscle disorders characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk and neck muscles.
Alternate Names: Dynamin-2, DYN2, DYNII, CMTDI1, CMTDIB, DI-CMTB, DNM2
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: P50570
Antigen: Purified recombinant fragment of Dynamin-2 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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