EBV-EA p55;50 (clone 1108-1), anti-human

Source:
A BALB/c mouse was immunized with immunoprecipitated EBV early antigens.
Fusion partner: NS-0.

Specifications:
1108-1 Recognizes a 55-50 kDa polypeptide associated with the early antigen of Epstein-Barr virus (EBV). p55 Has beenshown to be a phosphoprotein and p55-50has strong DNA-binding activity preferentially to single-stranded DNA.Epstein-Barr virus is the causitive agent of infectious mononucleosis and is associated with two human neoplasms, Burkitt's lymphoma and nasopharyngeal carcinoma. Several EBV-related antigens associated with early or late functions of the viral genome have been identified. The early antigen may be virally or chemically induced in EBV infected cells and is the first detectable marker of EBV infection in human cells.

Species reactivity:
Positive: human.

Applications:
Demonstration of EBV-EA.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Immunoprecipitation: +
Paraffin sections: -

Positive control: Chemically induced Raji cells.

References:
- Epstein, AL. J. Virol.50: 372-379 (1984)