EhpB6 (clone 2A6B9), anti-human
€394.00
In stock
SKU
252753
Catalog Nr.: 252753
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, IHC
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: WB, IHC
Protein Family: Enzymes, Protein Kinases
Pathway and Disease: Cancers, Cell Growth and Death
Description:
EphB6 (EPH receptor B6) is a 1006-amino acid protein (~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.
Alternate Names: Ephrin type-B receptor 6, HEP, Tyrosine-protein kinase-defective receptor EPH-6, EPHB6
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: O15197
Antigen: Purified recombinant fragment of EphB6(aa601-750) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Cell Growth and Death
Description:
EphB6 (EPH receptor B6) is a 1006-amino acid protein (~ 110 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. Eph receptors and ephrin ligands are membrane-bound cell-cell communication molecules with well-defined functions in development. EphB6 is expressed both in a variety of embryonic and adult tissues. EphB6 is a unique member in the Eph family of receptor tyrosine kinases in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. EphB6 can both positively and negatively regulate cell adhesion and migration and tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition.
Alternate Names: Ephrin type-B receptor 6, HEP, Tyrosine-protein kinase-defective receptor EPH-6, EPHB6
Application Notes: WB: 1:500-1:2000; IHC: 1:200-1:1000
Accession No.: O15197
Antigen: Purified recombinant fragment of EphB6(aa601-750) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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