EIF2C4 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors

Pathway and Disease: Translation

Description:
Protein argonaute-4 (EIF2C4) is required for RNA-mediated gene silencing (RNAi). EIF2C4 binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. EIF2C4 lacks endonuclease activity and does not appear to cleave target mRNAs. EIF2C4 is also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).

Alternate Names: Protein argonaute-4, Argonaute4 hAgo4, Eucaryotic translation initiation factor 2C 4, eIF-2C 4, eIF2C 4, EIF2C4, AGO4, KIAA1567

Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:500; IHC: 1:50-1:200

Accession No.: Q9HCK5

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human EIF2C4.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.