EMP-1 polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels

Pathway and Disease: Neurodegenerative Disorders, Nervous and Sensory Systems; Signaling Molecules and Interaction

Description:
Tumor-associated membrane protein (EMP-1) is a glycoprotein that is highly expressed in brain tumor cells but not in normal brain. It is also expressed at high levels in undifferentiated embryonic stem cells, but markedly down-regulated in these cells after their differentiation into embryoid bodies. The EMP amino acid sequence bears high homology to the growth arrest specific protein PMP22/GAS-3, which is involved in several human peripheral neuropathies.

Alternate Names: EMP1, EMP-1, Epithelial membrane protein 1, Tumor-associated membrane protein, CL-20, Protein B4B, TMP

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P47801

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse EMP-1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA, 25% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1] Yu X. et al. 2013. Histopathy. doi: 10.1111/his.12211.
[2] Jin P. et al. 2013. Asian Rhinology J. 1: 21-5.