Erk1/2 (clone 3F8), anti-human, mouse
€394.00
In stock
SKU
252974
Catalog Nr.: 252974
Size: 0.1 ml
Isotype: Mouse IgG2b
Applications: WB, FC
Size: 0.1 ml
Isotype: Mouse IgG2b
Applications: WB, FC
Protein Family: Enzymes, Protein Kinases
Pathway and Disease: Cancers, Cell Communication, Cell Motility, Development and Behavior, Endocrine System, Immune System, Metabolic Disorders, Nervous and Sensory Systems, Signal Transduction
Description:
ERK1 and ERK2 (Extracellular signal-regulated kinase 1 and 2) are members of the MAP kinase signal transduction pathway. The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42 encoded by ERK1 and ERK2 respectively. Both kinases are regulated by dual specific phosphorylation on tyrosine and threonine in response to insulin and NGF. ERK1 and ERK2 are involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1.
Alternate Names: ERK-1, Mitogen-activated protein kinase 3, Extracellular signal-regulated kinase 1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK1, p44-ERK1, ERT2, p44-MAPK, Microtubule-associated protein 2 kinase, MAPK3, ERK1, PRKM3, and for ERK-2, Mitogen-activated protein kinase 1, Extracellular signal-regulated kinase 2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK2, p42-MAPK, ERT1, MAPK1, ERK2, PRKM1, PRKM2
Application Notes: WB: 1:500-1:2000; FC: 1:200-1:400
Accession No.: P27361, P28482
Antigen: Purified recombinant fragment of human MAPK1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Cancers, Cell Communication, Cell Motility, Development and Behavior, Endocrine System, Immune System, Metabolic Disorders, Nervous and Sensory Systems, Signal Transduction
Description:
ERK1 and ERK2 (Extracellular signal-regulated kinase 1 and 2) are members of the MAP kinase signal transduction pathway. The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42 encoded by ERK1 and ERK2 respectively. Both kinases are regulated by dual specific phosphorylation on tyrosine and threonine in response to insulin and NGF. ERK1 and ERK2 are involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1.
Alternate Names: ERK-1, Mitogen-activated protein kinase 3, Extracellular signal-regulated kinase 1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK1, p44-ERK1, ERT2, p44-MAPK, Microtubule-associated protein 2 kinase, MAPK3, ERK1, PRKM3, and for ERK-2, Mitogen-activated protein kinase 1, Extracellular signal-regulated kinase 2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK2, p42-MAPK, ERT1, MAPK1, ERK2, PRKM1, PRKM2
Application Notes: WB: 1:500-1:2000; FC: 1:200-1:400
Accession No.: P27361, P28482
Antigen: Purified recombinant fragment of human MAPK1 expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
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