ERK1/2 polyclonal, anti-human, mouse, rat

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Signal Transduction, Cell Communication, Cell Growth and Death, Cell Motility, Immune System, Endocrine System, Nervous and Sensory Systems, Development and Behavior, Cancers, Neurodegenerative Disorders, Metabolic Disorders, Infectious Diseases

Description:
Mitogen-activated protein kinase 3 (ERK1/2) is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. ERK1/2 is activated by tyrosine phosphorylation in response to insulin and NGF.

Alternate Names: ERK-1, Mitogen-activated protein kinase 3, Extracellular signal-regulated kinase 1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK1, p44-ERK1, ERT2, p44-MAPK, Microtubule-associated protein 2 kinase, MAPK3, ERK1, PRKM3, and for ERK-2, Mitogen-activated protein kinase 1, Extracellular signal-regulated kinase 2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK2, p42-MAPK, ERT1, MAPK1, ERK2, PRKM1, PRKM2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P27361; P28482

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ERK1/2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.