ESAT-6 Mycobacterium (clone 11 G4), anti-bacteria
€1,057.00
In stock
SKU
250322
Catalog Nr.: 250322
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Protein Family: Cellular Antigens
Pathway and Disease: Infectious Diseases, Immune System
Description:
ESAT-6 (6-kDa early secretory antigenic target) from Mycobacterium tuberculosis H37Rv (ATCC 27294) is a secreted tubercular protein that forms a dominant target for cell-mediated immunity in the early phase of infection. The deduced amino acid sequence indicates a molecular mass of 10 kDa. It is present in M. tuberculosis, virulent strains of M. bovis, and in M. flavescens, M. kansasii, M. marinum,and M. szulgai, but not in avirulent M. bovis BCG substrains. This antibody reacts with ESAT-6 in immunoblotting after SDS-PAGE of short-term culture filtrates of M. tuberculosis and virulent strains of M. bovis. The antibody cross-reacts with MPB64 (26 kDa) from certain BCG substrains, with the A, B, and C components of the antigen 85 complex and with MPT51.
Alternate Names: 6 kDa early secretory antigenic target
Application Notes: Product Cat. No. 250322 reacts with PPD, culture filtrate, cytosol and cell wall preparations from M. tuberculosis. E: 1:3,200; WB: 1:500
Accession No.: P0A564
Antigen: Purified protein derivative (PPD) of tuberculin from M. tuberculosis conjugated with thimerosal N-hydroxysuccinimide ester and adsorbed to aluminum hydroxide gel (4).
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Infectious Diseases, Immune System
Description:
ESAT-6 (6-kDa early secretory antigenic target) from Mycobacterium tuberculosis H37Rv (ATCC 27294) is a secreted tubercular protein that forms a dominant target for cell-mediated immunity in the early phase of infection. The deduced amino acid sequence indicates a molecular mass of 10 kDa. It is present in M. tuberculosis, virulent strains of M. bovis, and in M. flavescens, M. kansasii, M. marinum,and M. szulgai, but not in avirulent M. bovis BCG substrains. This antibody reacts with ESAT-6 in immunoblotting after SDS-PAGE of short-term culture filtrates of M. tuberculosis and virulent strains of M. bovis. The antibody cross-reacts with MPB64 (26 kDa) from certain BCG substrains, with the A, B, and C components of the antigen 85 complex and with MPT51.
Alternate Names: 6 kDa early secretory antigenic target
Application Notes: Product Cat. No. 250322 reacts with PPD, culture filtrate, cytosol and cell wall preparations from M. tuberculosis. E: 1:3,200; WB: 1:500
Accession No.: P0A564
Antigen: Purified protein derivative (PPD) of tuberculin from M. tuberculosis conjugated with thimerosal N-hydroxysuccinimide ester and adsorbed to aluminum hydroxide gel (4).
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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