EV450 Anti-Human CD326 Antibody [clone 9C4]
€0.00
In stock
SKU
E-AB-F1163Q
Catalog Number: E-AB-F1163Q
Reactivity: Human, Clone: 9C4
Isotype: Mouse IgG2b, κ, Conjugation: EV450
Applications: FCM
Datasheet, Questions? Contact us!
Reactivity: Human, Clone: 9C4
Isotype: Mouse IgG2b, κ, Conjugation: EV450
Applications: FCM
Datasheet, Questions? Contact us!
Background:
CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.
Synonyms:
EpCAM, Ep-CAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
Swissprot: P16422
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage:
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Alternative for product with catalog number:
324219, 324220, 369821, 369822
CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.
Synonyms:
EpCAM, Ep-CAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
Swissprot: P16422
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage:
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Alternative for product with catalog number:
324219, 324220, 369821, 369822
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