EZH1 polyclonal, anti-human, mouse, rat
€347.00
In stock
SKU
254454
Catalog Nr.: 254454
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IF
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC, IF
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction, Transcription
Description:
EZH1 was initially identified as a homolog of the drosophila Enhancer of Zeste through transcription mapping of chromosome 17q21. Both EZH1 and the related protein EZH2 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair. Multiple isoforms of EZH1 are known, however this antibody does not react with EZH2.
Alternate Names: Enhancer of zeste homolog 1, histone-lysine-N-methylase EZH1, KMT6B, ENX2
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IF: 1:50-1:200
Accession No.: AAC50778
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human EZH1.
Format: Each vial contains 0.1 ml IgG (1 mg/ml) in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction, Transcription
Description:
EZH1 was initially identified as a homolog of the drosophila Enhancer of Zeste through transcription mapping of chromosome 17q21. Both EZH1 and the related protein EZH2 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair. Multiple isoforms of EZH1 are known, however this antibody does not react with EZH2.
Alternate Names: Enhancer of zeste homolog 1, histone-lysine-N-methylase EZH1, KMT6B, ENX2
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IF: 1:50-1:200
Accession No.: AAC50778
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human EZH1.
Format: Each vial contains 0.1 ml IgG (1 mg/ml) in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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