Factor B (clone 6G11 ), anti-human
€747.00
In stock
SKU
250293
Catalog Nr.: 250293
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Protein Family: Enzymes, Peptidases
Pathway and Disease: Immune System
Description:
Factor B is a component of the alternative pathway of complement activation. The protein consists of a single polypeptide chain of molecular mass 93 kDa, and has a concentration in plasma of approximately 200 ,mg/mL. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Together with C3b, Bb forms the alternative pathway C3 convertase C3bBb. This antibody is specific for the Ba fragment of human factor B.
Alternate Names: C3/C5 convertase, Properdin factor B, Glycine-rich beta glycoprotein, GBG, PBF4
Application Notes: Product Cat. No. 250293 reacts strongly with human factor B. Strong reaction is seen when coated directly onto the microtiter well and also when used as detection antibody in sandwich ELISA with a polyclonal capture antibody against factor B. In Western blot, Product Cat. No. 250293 reacts with the Ba fragment of factor B in its non-reduced form only. E: 1:1,600; WB: 1:500
Accession No.: P00751
Antigen: Complemen factor B purified from human plasma and adsorbed to aluminum hydroxide gel
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Immune System
Description:
Factor B is a component of the alternative pathway of complement activation. The protein consists of a single polypeptide chain of molecular mass 93 kDa, and has a concentration in plasma of approximately 200 ,mg/mL. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Together with C3b, Bb forms the alternative pathway C3 convertase C3bBb. This antibody is specific for the Ba fragment of human factor B.
Alternate Names: C3/C5 convertase, Properdin factor B, Glycine-rich beta glycoprotein, GBG, PBF4
Application Notes: Product Cat. No. 250293 reacts strongly with human factor B. Strong reaction is seen when coated directly onto the microtiter well and also when used as detection antibody in sandwich ELISA with a polyclonal capture antibody against factor B. In Western blot, Product Cat. No. 250293 reacts with the Ba fragment of factor B in its non-reduced form only. E: 1:1,600; WB: 1:500
Accession No.: P00751
Antigen: Complemen factor B purified from human plasma and adsorbed to aluminum hydroxide gel
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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