FBXW8 polyclonal, anti-human

Protein Family: Enzymes, Ubiquitins

Pathway and Disease: Folding, Sorting and Degradation

Description:
F-box/WD repeat-containing protein 8 (FBXW8) is a substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteosomal degradation of target proteins. FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box.

Alternate Names: F-box/WD repeat-containing protein 8, F-box and WD-40 domain-containing protein 8, F-box only protein 29, FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6

Application Notes: E: 1:1,000-1:16,000; WB: 1:100-1:1,000

Accession No.: Q8N3Y1

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human FBXW8.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2%BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.