FGB (clone 1F9), anti-human
€363.00
In stock
SKU
252888
Catalog Nr.: 252888
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB
Protein Family: CAM Ligands, Cell Adhesion Molecules
Pathway and Disease: Signaling Molecules and Interaction; Immune System
Description:
FGB (Fibrinogen beta chain) is part of the blood coagulation system. It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Alternate Names: Fibrinogen beta chain, FGB
Application Notes: E: 1:10,000-1:20,000; WB: 1:500-1:2000
Accession No.: P02675
Antigen: Purified recombinant fragment of human FGB (aa30-300) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction; Immune System
Description:
FGB (Fibrinogen beta chain) is part of the blood coagulation system. It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Alternate Names: Fibrinogen beta chain, FGB
Application Notes: E: 1:10,000-1:20,000; WB: 1:500-1:2000
Accession No.: P02675
Antigen: Purified recombinant fragment of human FGB (aa30-300) expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
| Is Featured? | No |
|---|
Write Your Own Review