Fibrinogen (clone 1D6), anti-human
€747.00
In stock
SKU
250310
Catalog Nr.: 250310
Size: 0.2 mg
Isotype: Mouse IgG1
Applications: E, WB
Size: 0.2 mg
Isotype: Mouse IgG1
Applications: E, WB
Protein Family: CAM Ligands, Cell Adhesion Molecules
Pathway and Disease: Signaling Molecules and Interaction, Immune System
Description:
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Fibrinogen consists as a dimer of 3 pairs of non-identical chains Aa (Mr= 66,800), Bb (Mr= 52,000) and g (Mr=46,500) cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. MW is 340 kDa. Concentration in human plasma is 2-3 mg/ml. This antibody is specific for human fibrinogen.
Alternate Names: Fibrinogen alpha chain, FGA
Application Notes: Product Cat. No. 250310 reacts strongly with fibrinogen in ELISA with factor VIII HP directly coated onto the microtiterwell, and also when tested in sandwich ELISA in combination with a polyclonal antibody against fibrinogen. Product Cat. No. 250310 reacts in western blot with fibrinogen in non-reduced form only. E: 1:8,000; WB: 1:500
Accession No.: P02671
Antigen: Fibrinogen isolated from human plasma
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Gonzalez R et al. 2011.Analytical Biochemistry. 414(1): 99-102. PMID# 21371419 .
Pathway and Disease: Signaling Molecules and Interaction, Immune System
Description:
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Fibrinogen consists as a dimer of 3 pairs of non-identical chains Aa (Mr= 66,800), Bb (Mr= 52,000) and g (Mr=46,500) cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. MW is 340 kDa. Concentration in human plasma is 2-3 mg/ml. This antibody is specific for human fibrinogen.
Alternate Names: Fibrinogen alpha chain, FGA
Application Notes: Product Cat. No. 250310 reacts strongly with fibrinogen in ELISA with factor VIII HP directly coated onto the microtiterwell, and also when tested in sandwich ELISA in combination with a polyclonal antibody against fibrinogen. Product Cat. No. 250310 reacts in western blot with fibrinogen in non-reduced form only. E: 1:8,000; WB: 1:500
Accession No.: P02671
Antigen: Fibrinogen isolated from human plasma
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Gonzalez R et al. 2011.Analytical Biochemistry. 414(1): 99-102. PMID# 21371419 .
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