Fibronectin (Cell Binding Site) (clone 568), anti-human, mouse

Source:
A BALB/c mouse was immunized with a high molecular fraction of proteins secreted by cultured human fibroblasts.
Fusion partner: P3-C63-Ag8.653.

Specifications:
568 Reacts with the 8th type III repeat in the cell-binding domain of human fibronectin (220 kDa monomer; 440 kDa, dimer). Fibronectins are present in basement membranes, intestinal connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors.

Species reactivity:
Positive: human, mouse. Negative: dog, ferret.

Applications:
568 Is excellent for staining of formalin-fixed, paraffin-embedded tissues. 568 Also works well in immunofluorescence tests.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Paraffin sections: Tris/EDTA
Western blot: +

Positive control: Paraffin sections of normal human breast, MCF-7 cells or A431 cell lysate.

References:
- Christensen, L. et al, APMIS98(7): 615-623 (1990).
- Christensen, L. et al, APMISsuppl. 26: 1-39 (1992).
- Yong, JL. et al, Int J Clin Exp Pathol3(2): 210-216 (2010).