Fibronectin (clone TV-1), anti-human, mouse, rat, pig

Source:
A BALB/c mouse was immunized with a T-cell lymphoma biopsy.

Specifications:
TV-1 recognizes fibronectin in frozen and paraffin sections of human, pig, mouse and rat tissues. Specifically, it stains this extracellular adhesive glycoprotein in connective tissues andblood vessels. TV-1 does not recognize the soluble dimeric form of fibronectin (plasma fibronectin) but strongly stains matrix fibronectin in tissues. Cellular fibronectin is widely distributed in the stroma of many malignant tumors.

Species reactivity:
Positive: human, mouse, pig, rat.

Applications:
TV-1 is recommended for detection of human fibronectin by Western blot, immunofluorescence tests and immunohistochemistry.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Paraffin sections: Tris/EDTA
Western blot: +

Positive control: Connective tissue, blood vessels.

References:
- Epstein, AL. et al. Cancer Res. 55(12): 2673-80 (1995)