FLT-3 Ligand mouse active recombinant protein
€295.00
In stock
SKU
600183
Protein Family: Cytokines
Pathway and Disease: Immune System, Signaling Molecules and Interaction, Cancers, Cell Growth and Death, Signal Transduction
Alternate Names: SL cytokine, Fms-related tyrosine kinase receptor 3 ligand, FLT3L, Flt3 ligand, FLT3LGDescription:
Fms-related tyrosine kinase receptor 3 ligand (Flt3 ligand, FLT3LG) binds to Fms-Like Tyrosine Kinase-3 (FLT-3). Mouse FLT3 ligand stimulates the proliferation of cells expressing mouse FLT-3 receptors. The effects of FLT-3 ligand are synergized by coexpression of G-CSF, GM-CSF, M-CSF, IL3 and SCF. FLT-3 ligand promotes long-term expansion and differentiation of mouse pro-B-cells in the presence of IL7 or in combination of IL7 and IL3. Recombinant Mouse Flt3-Ligand produced in E. coli is a non-glycosylated polypeptide chain containing 144 amino acids with a MW of 16,431 Da.
Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Applications: E, WB
Application Notes:
Recombinant mouse Flt-3 Ligand is fully biologically active when compared to standards. The ED50, calculated by the dose-dependent proliferation of mouse AML5 cells is less than 7.0 ng/ml.
Accession No.: P49772
MW: 16431 Da
Sequence:
MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
Purity:
Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
Pathway and Disease: Immune System, Signaling Molecules and Interaction, Cancers, Cell Growth and Death, Signal Transduction
Alternate Names: SL cytokine, Fms-related tyrosine kinase receptor 3 ligand, FLT3L, Flt3 ligand, FLT3LGDescription:
Fms-related tyrosine kinase receptor 3 ligand (Flt3 ligand, FLT3LG) binds to Fms-Like Tyrosine Kinase-3 (FLT-3). Mouse FLT3 ligand stimulates the proliferation of cells expressing mouse FLT-3 receptors. The effects of FLT-3 ligand are synergized by coexpression of G-CSF, GM-CSF, M-CSF, IL3 and SCF. FLT-3 ligand promotes long-term expansion and differentiation of mouse pro-B-cells in the presence of IL7 or in combination of IL7 and IL3. Recombinant Mouse Flt3-Ligand produced in E. coli is a non-glycosylated polypeptide chain containing 144 amino acids with a MW of 16,431 Da.
Source: E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Applications: E, WB
Application Notes:
Recombinant mouse Flt-3 Ligand is fully biologically active when compared to standards. The ED50, calculated by the dose-dependent proliferation of mouse AML5 cells is less than 7.0 ng/ml.
Accession No.: P49772
MW: 16431 Da
Sequence:
MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
Purity:
Purity > 98% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Format:
Each vial contains 10 ug of lyophilized protein. Reconstitute with 0.1 ml sterile deionized water for a final concentration of 0.1 mg/ml.
Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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