Fractalkine human active recombinant protein

Fractalkine human active recombinant protein

€295.00
In stock
SKU
600325
Catalog Number: 600325
Size: 0.02 mg
Datasheet
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Protein Family: Cytokines

Pathway and Disease: Signaling Molecules and Interaction, Immune System

Alternate Names: Neurotactin, Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Small-inducible cytokine D1, CX3CL1, FKN, NTT, SCYD1Description:
Fractalkine, also known as CX3CL1, is an atypical chemokine that was the first of a fourth chemokine motif (CX3C). It is thought to function as a T cell and monocyte chemotractant and is produced by non-haemopoietic cells. Fractalkine is made in a soluble and membrane bound form in activated endothelial cells which is thought to promote adhesion of leukocytes. Human Fractalkine is produced in E.coli. Recombinant human Fractalkine is a non-glycosylated protein, containing 76 amino acids, with a molecular weight of 8.6 kDa.

Source: E. coli. Endotoxin level as measured by LAL is <0.05ng/ug or <0.5EU/ug.

Applications: E, WB

Application Notes:
The activity is determined by the dose dependent chemotaxis of human PBMCs and is typically starting between 10-100 ng/mL. Specific activity: 1 x 10e5 units/mg

Accession No.: P78423

MW: 8600 Da

Sequence:
QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG

Purity:
Purity > 95% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by UV spectroscopy at 280 nm and analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.

Format:
Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Storage: Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.
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