GABAA Receptor alpha-2 polyclonal, anti-human, mouse, rat, bovine, dog, monkey, zebrafish
€418.00
In stock
SKU
253141
Catalog Nr.: 253141
Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB
Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB
Protein Family: Receptors and Channels
Pathway and Disease: Nervous and Sensory Systems
Description:
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a chloride channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex.
Alternate Names: Gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2, Gabra2, Gabra-2
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: P23576
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat GABAA receptor alpha 2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems
Description:
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a chloride channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex.
Alternate Names: Gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2, Gabra2, Gabra-2
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: P23576
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat GABAA receptor alpha 2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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