GABAA Receptor gamma-2 polyclonal, anti-human, mouse, rat, bovine, chicken, dog, monkey, Xenopus, zebrafish
€418.00
In stock
SKU
253154
Catalog Nr.: 253154
Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB, IHC
Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB, IHC
Protein Family: Receptors and Channels
Pathway and Disease: Nervous and Sensory Systems
Description:
Gamma-aminobutyric acid receptor subunit gamma-2 (GABAA Receptor, g2) is a receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The GABA receptor is pentameric in structure, and there are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. It has recently been suggested that PKC regulates the sensitivity of GABAA a1b2g2 receptors to ethanol and benzodiazepines through phosphorylation of serine 327 in the large intracellular loop of g2.
Alternate Names: Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, Gabrg2, GABAA Receptor, g2
Application Notes: E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:400
Accession No.: P18508
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within rat GABAA receptor gamma 2.
Format: Each vial contains 0.1 ml of crude serum with 0.09% sodium azide.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems
Description:
Gamma-aminobutyric acid receptor subunit gamma-2 (GABAA Receptor, g2) is a receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The GABA receptor is pentameric in structure, and there are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. It has recently been suggested that PKC regulates the sensitivity of GABAA a1b2g2 receptors to ethanol and benzodiazepines through phosphorylation of serine 327 in the large intracellular loop of g2.
Alternate Names: Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, Gabrg2, GABAA Receptor, g2
Application Notes: E: 1:500-1:1,000; WB: 1:1,000; IHC: 1:400
Accession No.: P18508
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within rat GABAA receptor gamma 2.
Format: Each vial contains 0.1 ml of crude serum with 0.09% sodium azide.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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