GABAA Receptor gamma-2 (Ser327) polyclonal, anti-rat, bovine, dog, chicken, xenopus, zebrafish
€440.00
In stock
SKU
252542
Catalog Nr.: 252542
Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB
Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB
Protein Family: Receptors and Channels
Pathway and Disease: Nervous and Sensory Systems
Description:
Gamma-aminobutyric acid receptor subunit gamma-2 (GABAA Receptor, g2) is a receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The GABA receptor is pentameric in structure, and there are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. It has recently been suggested that PKC regulates the sensitivity of GABAA a1b2g2 receptors to ethanol and benzodiazepines through phosphorylation of serine 327 in the large intracellular loop of g2.
Alternate Names: Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, Gabrg2, GABAA Receptor, g2
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: P18508
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser327 of rat GABAA receptor, g2.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems
Description:
Gamma-aminobutyric acid receptor subunit gamma-2 (GABAA Receptor, g2) is a receptor for gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. The GABA receptor is pentameric in structure, and there are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. It has recently been suggested that PKC regulates the sensitivity of GABAA a1b2g2 receptors to ethanol and benzodiazepines through phosphorylation of serine 327 in the large intracellular loop of g2.
Alternate Names: Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, Gabrg2, GABAA Receptor, g2
Application Notes: E: 1:1,000; WB: 1:1,000
Accession No.: P18508
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser327 of rat GABAA receptor, g2.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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