Gastric Inhibitory Polypeptide (clone ), anti-human

Protein Family: Hormones

Pathway and Disease: Endocrine System, Signaling Molecules and Interactions

Description:
Human gastric inhibitory polypeptide (GIP) is a 42-amino-acid peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from approximately 50% identity for glucagon to 30% identity for GLP-2). This antibody binds human GIP but does not cross-react with GLP-1 or -2, PACAP, glucagon or VIP. Cross-reactivity with porcine GIP has not been determined.

Alternate Names: Gastric inhibitory polypeptide, GIP, glucose-dependent insulinotropic polypeptide

Application Notes: The dilution guideline for ELISA is based on use of Product Cat. No. 250232 as detection antibody for antigen coated at 2 µg/ml. In addition Product Cat. No. 250232 binds free GIP in solution. E: 1:1,000

Accession No.: P09681

Antigen: Synthetic human gastric inhibitory polypeptide coupled to carrier

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.