GFAP (clone 6A6), anti-human, rat
€429.00
In stock
SKU
253067
Catalog Nr.: 253067
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC, IF
Size: 0.1 ml
Isotype: Mouse IgG1
Applications: E, WB, IHC, IF
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Neurodegenerative Disorders
Description:
GFAP (Glial fibrillary acidic protein) is a class-III intermediate filament. It is a cell-specific marker that distinguishes astrocytes from other glial cells during the development of the central nervous system (CNS). Defects in GFAP are a cause of Alexander disease a rare disorder of the CNS described as leukoencephalopathy. GFAP is expressed in the cortex and hippocampus, and its expression decreases following acute and chronic corticosterone treatment.
Alternate Names: Glial fibrillary acidic protein, GFAP
Application Notes: E: 1:10,000; WB: 1:200-1:1000; IHC: 1:200-1:1000; IF: 1:200-1:1000;
Accession No.: P14136
Antigen: Purified recombinant fragment of human GFAP expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Product Citations:
[1] Maturana CJ et al. 2016. Dev Neurobiol. 77(5): 625-642. PMID 27314460.
Pathway and Disease: Neurodegenerative Disorders
Description:
GFAP (Glial fibrillary acidic protein) is a class-III intermediate filament. It is a cell-specific marker that distinguishes astrocytes from other glial cells during the development of the central nervous system (CNS). Defects in GFAP are a cause of Alexander disease a rare disorder of the CNS described as leukoencephalopathy. GFAP is expressed in the cortex and hippocampus, and its expression decreases following acute and chronic corticosterone treatment.
Alternate Names: Glial fibrillary acidic protein, GFAP
Application Notes: E: 1:10,000; WB: 1:200-1:1000; IHC: 1:200-1:1000; IF: 1:200-1:1000;
Accession No.: P14136
Antigen: Purified recombinant fragment of human GFAP expressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Product Citations:
[1] Maturana CJ et al. 2016. Dev Neurobiol. 77(5): 625-642. PMID 27314460.
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