GFAP (clone GA-8), anti-human, mouse, rat, pig
€378.00
In stock
SKU
251752
Catalog Nr.: 251752
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB, IHC
Size: 0.1 mg
Isotype: Mouse IgG1
Applications: E, WB, IHC
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Nervous and Sensory Systems, Neurodegenerative Disorders
Description:
Glial fibrillary acidic protein (GFAP), a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Defects in GFAP are a cause of Alexander disease (ALEXD). Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes.
Alternate Names: Glial fibrillary acidic protein, GFAP
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P14136
Antigen: GFAP from pig spinal cord.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Nervous and Sensory Systems, Neurodegenerative Disorders
Description:
Glial fibrillary acidic protein (GFAP), a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Defects in GFAP are a cause of Alexander disease (ALEXD). Alexander disease is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes.
Alternate Names: Glial fibrillary acidic protein, GFAP
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P14136
Antigen: GFAP from pig spinal cord.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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