GFM1 polyclonal, anti-human

Protein Family: Enzymes, Translation Factors

Pathway and Disease: Translation

Description:
Elongation factor G, mitochondrial (GFM1) is a mitochondrial GTPase that plays a central role in protein elongation by promoting the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. GFM1 does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Defects in GFM1 are the cause of combined oxidative phosphorylation deficiency type 1 (COXPD1), a condition that leads to early fatal progressive hepatoencephalopathy.

Alternate Names: Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1, hEFG1, GFM1, EFG, EFG1, GFM

Application Notes: E: 1:10,000-1:50,000; WB: 1:100-1:500

Accession No.: Q96RP9

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GFM1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.